Events

HPLC 2015 Beijing, HPLC 2016 San Francisco, HPLC 2017 Jeju, HPLC 2018 Washington DC, HPLC 2019 Milan, HPLC 2020 San Diego

 

Keynote presentations and short courses/tutorials 

 

Eastern Analytical Symposium 2015-2020, EAS, Somerset or Princeton NJ 

 

Short courses in Modern HPLC and UHPLC 1 and 2.

 

Pittcon 2016-2020 

 

Short courses in Modern HPLC and UHPLC 1 and 2.

 

Amer. Chem. Soc. Online and at National Meetings 2015 -2020

 

Short courses in Modern HPLC and UHPLC 1 and 2.

Books

 

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  1. M.W. Dong, HPLC and UHPLC for Practicing Scientists, 2nd Ed., Wiley, Hoboken, New Jersey, 2019.

  2. M.W. Dong, Modern HPLC for Practicing Scientists, Wiley, Hoboken, New Jersey, 2006
    (A best seller in HPLC with 8000 copies sold)

  3. Handbook of Pharmaceutical Analysis by HPLC, S. Ahuja and M.W. Dong (Eds), Elsevier/Academic Press, Amsterdam, the Netherlands, 2005.   

  4. J.L. DiCesare, M.W. Dong and L. S. Ettre. Introduction to High-Speed Liquid Chromatography, Perkin-Elmer, Norwalk, CT, 1981.

  5. D. Guillarme and M. W. Dong (Eds). UHPLC: Where we are ten years after its commercial introduction, Trends in Anal. Chem., 63, 1-188, 2014 (Special issue).

Regulatory Filings

 

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  1. Authored CMC sections of IND or IMPD of several new chemical entities for oncology (AKT-0068 (Phase 0 to 2b), IAP-0152 and IAP-0917)
     

  2. Contributed CMC filing to NDA/BLA (OxyContin NDA amendments and BLA for Kadcyla T-DM1 antibody-drug conjugate).

     

Short Courses Conducted
 

  1. HPLC/UHPLC I and II: EAS 2011-19 and  Pittcon 2012-19, ACS 2014-19, USP 2/2017, Chrom Forum Delaware Valley, 4/2017, Recro Pharma 12/18, City of Hope  9/18.
     

  2. Drug Discovery and Development Processes: EAS 2010, 14-17, Pittcon 2013, 15, 16. 19.
     

  3. Drug Quality Fundamentals, Quality Control of Small Molecule Drugs and Recombinant Biologics, UC Santa Cruz Extension, 2012-17, HPLC 2014, New Orleans, HPLC 2019, Milan, Pittcon 2015, EAS 2014-15.
     

  4. HPLC method development: EAS (2005-2010, 2015), HPLC 2016, PBSS 6/16, EAS 2016, HPLC 2018 Wash. DC.
     

  5. UHPLC and UHPLC in biopharmaceutical analysis (HPLC 2012 Anaheim, PBSS Bay Area, 6/16, NYS biotech symposium, 5/17).
     

  6. HPLC Operation and Troubleshooting, HPLC 2018 Wash. DC
     

  7. LC/MS tutorial, HPLC 2017 Jeju, Korea.


Technical Papers
 

120+ publications (>90 first-authored), Selected titles are shown here.
 

Separation Science in Drug Development

 

  1. M. Wong, B. Murphy, J. H. Pease and M. W. Dong, Separation Science in Drug Development, Part 1: High –Throughput Purification. LCGC North Am. 33(6), 402-413, 2015.

  2. B. Lin, J. H. Pease and M. W. Dong, Separation Science in Drug Development, Part 2: High –Throughput Characterization. LCGC North Am. 33(8), 534-545, 2015.

  3. M. W. Dong, Separation Science in Drug Development, Part 3: Analytical Development, LCGC North Am, 33(10), 764-775, 2015.

  4. D. Kou, L. Wigman, P. Yehl and M. W. Dong, Separation Science in Drug Development, Part 4: Quality Control, LCGC North Am. 33(12), 900-909, 2015.

 

UHPLC
 

  1. M.W. Dong, UHPLC 1: Perspectives and Instrumental Features, LCGC North Amer. 35(6), 374-381, 2017.

  2. M.W. Dong and D. Guillarme, UHPLC 2: Benefits, LCGC North Amer. 35(8), 486-495, 2017.

  3. M.W. Dong, UHPLC 3: Potential Issues, LCGC North Amer. 35(11), 818-823, 2017.
     

HPLC Instruments
 

  1. K. Shoykhet, K. Broeckhoven, and M.W. Dong, Modern HPLC Pumps: Perspectives, Principles, and Practice, LCGC North Amer. 37(6), 374-384, 2019.

  2. C. Paul, F. Steiner and M.W. Dong, HPLC Autosamplers: Perspectives, Principles, and Practices, LCGC North Amer. 37(8), xxx, 2019.

  3.  M.W. Dong and J. Wysocki, Ultraviolet detectors: Perspectives, Principles, and Practices, LCGC North Amer. 37(10), xxx, 2019.

  4. R. Mazzarese, S. M. Bird, M.W. Dong, Chromatography Data Systems: Perspective, Principles and Trends, LCGC North Amer. 37(12), xxx, 2019.

  5. M. W. Dong, New HPLC Systems and Related Products Introduced in 2018-2019: A Brief Review, LCGC North Am, 37(4), 252-259, 2019. (Same series from 2013-2018).
     

HPLC Method Development

 

  1. M.W. Dong, A Three-Pronged Template Approach for Rapid HPLC Method Development. LCGC North Am. 31(8), 612-621, 2013.

  2. M. W. Dong, A Universal Reversed-Phase HPLC Method for Pharmaceutical Analysis, LCGC North Am, 34(6), 408-419, 2016.

  3. M. W. Dong, D. Guillarme, S. Fekete, R. Rangelova, J. Richards, D. Prudhomme, and N. P. Chetwyn. High-resolution separations of complex pharmaceuticals by UHPLC: Case studies and quality control implications, LC GC North Am. 32(11), 868-76, 2014.

  4. M. W. Dong and K. Zhang, UHPLC in method development, Trend in Anal. Chem., 63, 21-30, 2014.
     

Bioscience
 

  1. R. E. Moore, K. Broster, K. Cook, K. D’Silva, E. Niederkofler, A.O. Bailey, J. Bones, and M. W. Dong. Antibody-Drug Conjugates: Perspectives and Characterization. LCGC North Am. 36(6), 362-274, 2018.

  2. T. Zhang, C. Quan and M.W. Dong, HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies. LCGC North Am. 32(10), 796-808, 2014.
     

Others

  1. M. W. Dong and B. E. Boyes, Modern Trends and Best Practices in Mobile-Phase Selection in Reversed-Phase Chromatography, LCGC North Am, 36(10), 752-767, 2018.

  2. M. W. Dong, Ten Common-Sense Corollaries in Pharmaceutical Analysis by HPLC, LCGC North Am, 36(8), 506-509, 2018.

  3. M. W. Dong and R. M. Woods, Quality Control Methodologies for Pharmaceutical Counterions, LCGC North Am, 34(10), 792-797, 2016.

  4. M. W. Dong, HPLC Column Standardization in Pharmaceutical Development: A Case Study, LCGC North Am, 34(8), 540-545, 2016.

  5. M.W. Dong, Seven Common Faux Pas in Modern HPLC. LCGC North Am. 32(8), 552-557, 2014.

  6. D. Guillarme and M. W. Dong. Newer developments in HPLC impacting pharmaceutical analysis: A brief review, Amer. Pharm. Rev. 16(4), 36-43, 2013.

  7. S. Fekete, D. Guillarme, and M.W. Dong, Superficially Porous Particles: Perspectives, Practices, and Trends. LCGC North Am. 32(6), 420-433, 2014.

  8. M.W. Dong, Myths in UHPLC. LCGC North Am. 31(10), 868-880, 2013.

  9. L. Dai, A. C. Quiroga, K. Zhang, H. B. Runes, D.T. Yazzie, K. Mistry, N. P. Chetwyn and M. W. Dong*, A Generic Headspace GC Method for Residual Solvents in Pharmaceuticals: Benefits, Rationale, and Adaptations for New Chemical Entities, LC.GC, 28(1), 54-66, 2010.