Examples of high-resolution UHPLC and the use of generic gradient methodologies in drug development from Michael's publications...
Flexibility of UHPLC
from fast analysis with good resolution to very high-resolution separation.
separation of drug product with 4 APIs
High-resolution separation by UHPLC
Retention marker solution and tox lot chromatograms
2-min and 5-min generic methods
separation of mixture of NCEs using generic UHPLC methodologies
2-min generic LC/MS method
Separation of 12 NCEs
Generic 10-min HPLC method
Cleaning verification method using LC/UV
Comparison of fast UHPLC
fully porous vs. SPP